Flow Cytometers for Multiparametric Cellular Profiling & Biomarker Discovery
Accurately quantify, classify, and isolate cells in suspension using advanced fluorescence-based multiparameter analysis.
Precision Cell Sorting and Phenotyping with Flow Cytometers
Flow cytometers are essential for analyzing the physical and biochemical properties of individual cells in suspension, enabling high-speed, multi-parameter quantification of cell populations. These instruments combine fluidics, optics, and electronics to identify, count, and sort cells based on markers such as size, granularity, and fluorescence labeling.
At Cellular Tissue Analysis, headquartered in Indianapolis, IN, we provide next-generation flow cytometry platforms that power immune profiling, rare cell detection, and intracellular staining workflows in clinical, academic, and industrial labs across North America.
Core Components:
Fluidics, Optics & Detection Systems
Hardware Modules
a. High-precision fluidics with sheath and sample flow control:
Motion & Position Sensors
Ensure stable and reproducible hydrodynamic focusing, enabling accurate alignment of cells for interrogation in high-throughput flow systems.
b. Multi-laser excitation (UV, violet, blue, yellow-green, red):
Optical & Imaging Sensors
Provide flexible and multiplexed fluorescence excitation, enabling simultaneous detection of multiple cellular markers with spectral precision.
c. Avalanche photodiodes and PMTs for signal detection:
Optical & Imaging Sensors
Deliver high sensitivity and fast response for detecting scattered light and fluorescence signals across multiple channels in flow cytometry.
Software Environment
- Compensation and gating algorithms
- Spectral unmixing for full-spectrum flow systems
- Batch processing and sample queuing
- Real-time population analysis and reporting
- Integration with LIMS and sample tracking systems
Connectivity & Data Handling
- High-throughput data export in FCS format
- Cloud storage and real-time result sharing
- Secure access for multi-site experiments
- Remote diagnostics and firmware upgrades
- AI-compatible data pipelines for cytometric modeling
Top Features of Our Flow Cytometry Platforms
Up to 30+ parameters per cell for deep phenotyping
High acquisition rates (100,000+ events/sec)
Minimal sample volume for rare cell studies
Cross-platform compatibility (research, GMP, GLP)
Plug-and-play configuration for customizable panels
Applications in Research and Clinical Science
Immunophenotyping in infectious disease and vaccine studies
Tumor microenvironment analysis in oncology
Hematological malignancy classification
Stem cell and regenerative medicine tracking
Cell cycle, apoptosis, and proliferation studies
Key Benefits
- Unmatched speed and resolution for complex assays
- Scalable from benchtop analyzers to industrial sorters
- Ideal for clinical trials, biomarker validation, and drug screening
- Enables rare event detection (CTCs, stem cells, T-regs)
- Minimal operator training with automated workflows
System Integration Capabilities
- Compatible with cell preparation robots and liquid handlers
- Integration with immunoassay platforms for correlative studies
- Standardized formats for multi-omics alignment
- Connectivity to data visualization suites (FlowJo, FCS Express)
- Direct link to cloud-hosted biobanks or hospital databases
Industries Served
- Hospital Diagnostic Laboratories
- Immunotherapy and Biopharma Companies
- Academic Immunology and Cell Biology Labs
- Contract Research Organizations (CROs)
- Clinical Trial Units and Transplant Centers
Compliance & Certification Standards
- FDA-cleared flow cytometry systems for IVD use
- CLIA-certified workflows for hematological profiling
- GMP/GLP-ready configurations for regulated environments
- CE-IVD and Health Canada-approved models
- ISO 15189-compatible validation documentation
Case Studies
U.S – Transplant Immunology Center, Los Angeles, CA
Adopted multi-laser cytometers to streamline donor-recipient HLA matching and T-cell subset profiling, reducing transplant rejection risks.
Canada – Oncology Research Lab, Montreal, QC
Deployed spectral flow cytometry to characterize immune infiltration in solid tumors, accelerating biomarker discovery for PD-1 therapies.
U.S – Vaccine Development Unit, Bethesda, MD
Used high-throughput analyzers for single-cell immune profiling post-vaccination. Enabled rapid stratification of responders vs. non-responders.
Advance your cell analysis capabilities with our flow cytometry platforms
Get in touch for system demos, specifications, and tailored deployment support.