Precision Microtomes & Cryostats for Confident , High-Quality Tissue Sectioning
Precision-Engineered Sectioning Systems for Accurate, Reproducible Results in Histology and Cryosectioning Applications
Precision Tissue Sectioning with Advanced Microtomy & Cryosectioning Systems
Microtomes and Cryostats are fundamental instruments for preparing thin tissue sections used in histological examination, immunostaining, and molecular assays. Microtomes are designed for paraffin-embedded specimens, while cryostats enable rapid frozen tissue sectioning for intraoperative or time-sensitive analysis.
At Cellular Tissue Analysis, based in Indianapolis, IN, our portfolio includes manual, semi-automated, and fully automated sectioning instruments that ensure accuracy, reproducibility, and user safety. Designed to minimize artifacts and maximize efficiency, these systems support a wide range of clinical and research applications.
Core Components of
Microtomes & Cryostats
Microtome Systems
a. Precision rotary or sliding microtomes:
Motion & Position Sensors
Track and control microtome blade movement to ensure consistent sectioning angles and cutting speed.
b. Rigid specimen clamps and holders:
Force & Clamping Sensors
Verify secure sample immobilization to prevent drift or vibration during slicing.
c. Micron-accurate thickness adjustment:
Linear Displacement Sensors
Enable ultra-precise control over section thickness, critical for reproducible histological cuts.
d. Disposable or reusable blade holders:
Blade Presence & Alignment Sensors
Detect blade installation and alignment status to ensure safety and section quality.
Cryostat Systems
Temperature- controlled freezing chambers (-20°C to -35°C):
Environmental Sensors
Maintain and monitor low-temperature stability essential for cryo-sectioning precision and tissue preservation.
Motorized specimen feed and retraction:
Motion & Position Sensors
Control the advancement and retraction of tissue blocks with high accuracy during sectioning.
Anti-roll plates and brush systems:
Contact & Force Sensors
Ensure proper pressure and alignment of anti-roll mechanisms to maintain flat, undistorted sections.
Touchscreen interface for cryo protocols:
Touch Sensors
Enable intuitive control and real-time adjustment of slicing parameters and temperature settings.
Control & Integration
- Digital displays for sectioning speed and thickness
- Integration with LIS for sample tracking
- Foot-pedal operation for hands-free sectioning
- Optional camera module for section preview
- Remote diagnostics and firmware updates.
Key Features
Micron-precision sectioning for reproducible results
Ergonomic design to reduce technician fatigue
High-throughput options with memory for presets
Quick-freeze function for optimal cryo embedding
Anti-vibration architecture for improved stability
Application Areas
Histological slide preparation
Frozen section analysis during surgery
Immunohistochemistry and molecular pathology
Tissue morphometry and biomarker research
Veterinary and plant biology research
Why Choose Our Microtomes & Cryostats
- Precision-engineered for routine and advanced histology
- Customizable presets for various tissue types
- Minimal maintenance with long-lasting components
- Built-in safety interlocks and blade guards
- Ideal for both teaching and clinical environments
Integration Capabilities
- Seamless data handoff to staining and imaging systems
- Barcode scanning for sample validation
- Network-enabled performance logging
- Compatible with digital pathology workflows
- Auto-calibration and blade usage tracking
Industries & End Users
- Hospital Pathology Labs and Operating Rooms
- Research Universities and Core Facilities
- Biotech & Pharmaceutical R&D Labs
- Contract Research Organizations (CROs)
- Veterinary Diagnostic Labs
Regulatory & Compliance Standards
- CE and ISO 13485–certified instruments
- Designed for CLIA and CAP-accredited workflows
- Compliance with ASCP and histotech best practices
- 21 CFR Part 11–ready software controls
- Internal QC tools for blade life and section metrics
North American Case Studies
U.S – Surgical Suite, Boston, MA
Cryostat system enabled real-time intraoperative frozen section diagnostics, reducing surgery time and improving pathology turnaround.
Canada – Research Hospital, Toronto, ON
Automated rotary microtomes improved consistency across paraffin sections, reducing staining variability and improving image analysis in cancer research.
U.S – Academic Pathology Lab, Houston, TX
Deployed a hybrid system integrating cryostat and microtomy for teaching applications, enhancing hands-on training in histotech programs.
Ready to upgrade your sectioning capabilities?
Contact Cellular Tissue Analysis for product demos, customization options, or a quote.